Changes in temperature can be a good way to measure a chemical or biological activity, providing both real-time (kinetic) or end-point (steady-state) information. There are numerous examples of the use of this method, termed calorimetry, in use throughout analytical sciences and biotechnology.
There are a number of reactions where very small amounts of heat are produced (or consumed). This might be because the sample is very small, or because the reaction itself does not result in a large energy change.
The Thermoelectric Sensor technology is a Nano-Calorimetric Sensor which measures very small changes in temperature. The IP provides a route to making the most sensitive calorimetric measurements (with a resolution of (0.1 mK). It is also ideally suited to analysis of small samples, associated with Lab-on-a-Chip methods.