Results For: Life Sciences

Showing 1 - 10 of 47 opportunities

  • Distributed Feedback Membrane Lasers for Counterfeit Protection and Authentication

    Extremely flexible, ultrathin and ultralow weight membrane lasers could be widely applied as security features on valued documents, banknotes and pharmaceuticals, and also a wide range of other high value branded products (spirits, perfumes).

    Expires: Created:
  • Biocatalysis of a novel fluorinated sugar [18-F]-FDR for PET imaging

    Combining the sequential use of 2 enzymes – fluorinase and nucleoside hydrolase – we have successfully produced a new radiotracer with potential as an imaging biomarker for PET scans. The fluorinase enzyme combines fluorine with S-adenosyl-L-methionine (SAM) to generate 5'-fluro-5'-deoxy...

    Expires: Created:
  • Calibration Device and method for Microcantilever Sensors

    Our technology provide the solution to enable the accurate calibration of microcantilever sensors used in Atomic force Microscopy (AFM), microfluidic applications, microelectromechanical systems (MEMS)and lab-on-a-chip technolgies.

    Expires: Created:
  • Novel target for Sickle Cell Disease & other haemolytic anaemias

    A novel therapeutic target for sickle cell disease and other haemolytic anaemias

    Expires: Created:
  • A potential therapeutic approach to Spinal Muscular Atrophy (SMA)

    The neurodegenerative inherited disease Spinal Muscular Atrophy (SMA) is the leading genetic cause of infant mortality, affecting 1:6,000 live births. SMA causes a loss of spinal motor neurons and is characterised by progressive muscular atrophy.

    Expires: Created:
  • Topology specific security holograms

    The most prominent high security holographic anti-counterfeiting techniques include dot-matrix holograms and electron beam defined holograms. Both techniques require laser illumination, and the image can be viewed with a screen, CCD, or directly by the human eye.

    Expires: Created:
  • One step prodrug trigger for targeted release of drugs

    A tetrazine small-molecule trigger for activating prodrugs has been developed. Active molecules, such as a therapeutic drug or imaging fluorophore, can be caged within a polymer nanoparticle for controlled release at a targeted site.

    Expires: Created:
  • Novel compound series to treat African trypanosomiasis

    Novel compound series of phosphofructokinase allosteric inhibitors which show excellent efficacy in vitro against the parasite and in mouse models of the disease in vivo. The well characterised inhibitors of this novel trypanosomiasis target have the potential to fill the unmet need for safe, cheap,...

    Expires: Created:
  • Potential treatment for allergic disease including severe steroid resistant asthma

    A novel approach shows promising results as a potential therapeutic for allergic conditions, including severe steroid resistant asthma. A peptide has been identified, HpARI, that inactivates and inhibits release of IL-33 a critical step in the development of allergic disease.

    Expires: Created:
  • Novel and selective inhibitors of SRC family kinases

    Novel compounds displaying high potency and selectivity toward SRC family kinases have been developed. The lead compound eCF506 displays subnanomolar potency against SRC, high selectivity over ABL kinase (1000-fold), optimal pharmacokinetic profile and in vivo target engagement.

    Expires: Created:

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