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Showing 1 - 10 of 70 opportunities
This novel technology provides attenuated Rift Valley fever viruses (RVFV) for use as vaccines and for the treatment and/or prevention of viral diseases and/or infection. Applied to RVFV (a member of the Phlebovirus genus of the Bunyaviridae) our technique results in modified, genetically distinct a...
Optical microfluidic sorting will allow biological or other matter to be sorted or fractionated by criteria including size, shape, density and refractive index. The technique may have the ability to sort matter from the scale of macro-molecules all the way up to large cells. In addition to the techn...
Bacterial cell-surface glycoconjugates are essential for survival of pathogenic bacteria and for interactions between bacteria and the host. Consequently, there is reason to believe that inhibitors directed against targets in the assembly of the cell-surface glycoconjugates may provide viable altern...
Some picornaviruses can cause mild illnesses, such as the common cold whilst others can give rise to serious conditions of the central nervous system, heart, skeletal muscle and liver.This assay allows the evaluation of new drug candidates to inhibit an interaction which is essential for picornavira...
A new “Optical micro-rotator” system incorporates apparatus for and a method of rotating microscopic using a beam of electromagnetic radiation. In order to rotate an object a microscopic, non-circularly symmetric distribution of electro-magnetic radiation is projected on to a region cont...
Many drugs are aimed at enhancing the therapeutic potential of nitric oxide (NO) in the cardiovascular system. These generally lack selectivity, hence there is a need to treat diseased tissues more specifically in order to restore their function.
Heriot-Watt University (Edinburgh, Scotland) has patent pending for a high power laser source in the femtosecond pulse range (sub 500-fs). This tunable ultrafast OPO laser source is suitable for application within micromachining, waveguide fabrication, and bio-imaging techniques such as multi-photon...
Extracts of valerian plants are widely and successfully used as sedatives. Preparations of plant materials are, however, variable in composition and in effectiveness.
Psoriasis is a skin disease characterised by inflammation and scaly lesions of the skin affecting 2-3% of the population in Europe and North America. Several different therapies are currently being used to treat psoriasis, but they all have the possibility of serious side effects.
Chronic inflammation contributes to a broad spectrum of diseases including arthritis, psoriasis, diabetes, allergy, connective tissue diseases, and heart disease. Despite the range of current therapeutics on offer, there is unmet clinical need as treatments such as corticosteroids, though often effe...