Results For: Life Sciences

Showing 21 - 30 of 47 opportunities

  • Rapid detection of antimicrobial resistance (AMR) & antibiotic sensitivity testing (AST)

    Antibiotics are often prescribed inappropriately leading to (1) patients remaining infected and failing to recover from bacterial infection, and (2) the spread of bacterial antibiotic resistance. Our laboratory prototype devices can provide accurate detection and quantification of bacterial suscepti...

    Expires: Created:
  • Rapid, sensitive counting of viable bacteria: the Molecular Bacterial Load Assay (MBLA)

    The Molecular Bacterial Load Assay (MBLA) provides a rapid and sensitive way to detect viable bacteria. MBLA opens up new applications in the diagnosis and treatment monitoring of a range of chronic bacterial infections, representing an opportunity to create a completely new platform of bacterial di...

    Expires: Created:
  • Particle Sorting by Dynamic Acoustic Travelling Waves

    This technology allows for effective separate suspended particles based on their stiffness, sorting by size and density. The separation uses dynamic acoustic fields enabling separation over a large distance, increasing the efficiency and throughput as compared to one operating on frequency shifting....

    Expires: Created:
  • Biomarker assay to enable safe corticosteroid withdrawal

    Using hypothesis-free metabolomics screening, a list of seven biomarkers has been identified that, when combined, are highly sensitive in predicting corticosteroid dose and, thus, the risk of adrenal insufficiency on corticosteroid withdrawal. Quantitative assays for these metabolites will create a ...

    Expires: Created:
  • Therapeutic target for treating vascular pathologies

    A long non-coding RNA target that regulates the proliferation of vascular smooth muscle cells, is present in the plasma of cardiovascular disease patients, and found at increased levels in unstable regions of atherosclerotic plaques. Therapeutic targeting of this molecule could inhibit vascular remo...

    Expires: Created:
  • Fluorescent Dyes for Enhancing Fingerprints

    Fingerprint detection on porous and/or wet surfaces is notoriously difficult. Current dyes, whether based on colour enhancement, scattering or fluorescence, do not bind to fingerprints on such substrates.

    Expires: Created:
  • Combination Treatment for MRSA Nasal Carriage and MRSA-infected Wounds

    The new treatment is a combination of a peptide (ranalexin) with bacteria cell wall-digesting protein (lysostaphin), which specifically targets and kills Staphylococcus aureus, including MRSA.

    Expires: Created:
  • Synergistic antifungal combination

    Candida species are a major cause of catheter-related nosocomial bloodstream infections. We have identified that the combination of an echinocandin antifungal with certain antimicrobial peptides results in potent, synergistic inhibition of yeast pathogens in vitro, so offering a potential combinatio...

    Expires: Created:
  • Fluorinase - an enzymatic process for the generation of organo-fluorine compounds

    Organo-fluorine compounds are of great importance in the pharmaceutical, fine chemical and agrochemical industries. For example, Prozac and 5-Fluorouracil are organo-fluorine compounds.

    Expires: Created:
  • Transforming Pharmaceutical Crystal Forms

    The innovation provides a gas-induced method for phase-transforming organic solids, such as pharmaceutical crystals. The inventive method subjects the polymorphs of pharmaceutical agents to various pressures of gases (such as CO2, N2O, and CH4) to induce phase transform with ease.

    Expires: Created:

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