Results For: Healthcare & Pharmaceuticals

Showing 1 - 10 of 54 opportunities

  • Novel target for Sickle Cell Disease & other haemolytic anaemias

    A novel therapeutic target for sickle cell disease and other haemolytic anaemias

    Expires: Created:
  • Chimaeric Innate Immune Receptors (CIIRS)

    A novel technology allowing targeting of cancer cells using the innate immune system

    Expires: Created:
  • A potential therapeutic approach to Spinal Muscular Atrophy (SMA)

    The neurodegenerative inherited disease Spinal Muscular Atrophy (SMA) is the leading genetic cause of infant mortality, affecting 1:6,000 live births. SMA causes a loss of spinal motor neurons and is characterised by progressive muscular atrophy.

    Expires: Created:
  • Topology specific security holograms

    The most prominent high security holographic anti-counterfeiting techniques include dot-matrix holograms and electron beam defined holograms. Both techniques require laser illumination, and the image can be viewed with a screen, CCD, or directly by the human eye.

    Expires: Created:
  • Improved experience for children and adults in visual field testing

    This optometry device uses a technique that is more natural for the patient than current gold standard visual field tests for diagnosing ophthalmologic conditions, resulting in more comfortable experience for patients and thus accessible to a wider patient group, including young children.

    Expires: Created:
  • One step prodrug trigger for targeted release of drugs

    A tetrazine small-molecule trigger for activating prodrugs has been developed. Active molecules, such as a therapeutic drug or imaging fluorophore, can be caged within a polymer nanoparticle for controlled release at a targeted site.

    Expires: Created:
  • Novel compound series to treat African trypanosomiasis

    Novel compound series of phosphofructokinase allosteric inhibitors which show excellent efficacy in vitro against the parasite and in mouse models of the disease in vivo. The well characterised inhibitors of this novel trypanosomiasis target have the potential to fill the unmet need for safe, cheap,...

    Expires: Created:
  • Potential treatment for allergic disease including severe steroid resistant asthma

    A novel approach shows promising results as a potential therapeutic for allergic conditions, including severe steroid resistant asthma. A peptide has been identified, HpARI, that inactivates and inhibits release of IL-33 a critical step in the development of allergic disease.

    Expires: Created:
  • Novel and selective inhibitors of SRC family kinases

    Novel compounds displaying high potency and selectivity toward SRC family kinases have been developed. The lead compound eCF506 displays subnanomolar potency against SRC, high selectivity over ABL kinase (1000-fold), optimal pharmacokinetic profile and in vivo target engagement.

    Expires: Created:
  • App for accurate detection and monitoring of delirium

    Delirium is an acute and severe deterioration in mental function, which affects attention and cognition and poses a significant health problem for older patients in hospital. DelApp is a novel app based cognitive test, which can objectively detect delirium in patients.

    Expires: Created:

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