Results For: "therapeutic"

Showing 1 - 10 of 11 opportunities

  • Strategy for Enhancing the Performance of Vaccines

    Researchers at the University of Dundee have designed and synthesised a novel, multifunctional protease inhibitor that has the potential to significantly enhance the performance of vaccines through proteolytic modulation.

    Expires: Created:
  • Activity based probe for Parkinson’s and other diseases

    Researchers at the University of Dundee have developed new activity based probes to profile enzyme activity linked to Parkinson’s and other diseases. Their discovery could provide novel biomarkers and new therapeutic targets, transforming diagnosis and treatment of disease.

    Expires: Created:
  • Therapeutic target for treating vascular pathologies

    A long non-coding RNA target that regulates the proliferation of vascular smooth muscle cells, is present in the plasma of cardiovascular disease patients, and found at increased levels in unstable regions of atherosclerotic plaques. Therapeutic targeting of this molecule could inhibit vascular remo...

    Expires: Created:
  • An early stage therapeutic target for bile duct cancer

    Notch-3 signalling is the key driver of tumour development in bile duct cancer, with Notch-3 receptor differentially overexpressed in comparison to other notch receptors. Therapeutic targeting of this receptor could provide anti-tumorigenic effects in patients, and act as a chemotherapeutic agent wi...

    Expires: Created:
  • Telomerase Promoter - Cancer Therapies

    The University of Glasgow has developed a (Ad-hTR-NTR) which has been extensively tested on Ovarian cancer cells.

    Expires: Created:
  • Macrophage-based cell therapy to treat acute liver injury

    A novel cell-based therapeutic intervention to treat patients suffering from acute episodes of liver injury. When injected into patients showing acute or drug-induced liver injury, alternatively-activated macrophages could promote liver repair, by reducing cell death, stimulating hepatocyte prolifer...

    Expires: Created:
  • One step prodrug trigger for targeted release of drugs

    A tetrazine small-molecule trigger for activating prodrugs has been developed. Active molecules, such as a therapeutic drug or imaging fluorophore, can be caged within a polymer nanoparticle for controlled release at a targeted site.

    Expires: Created:
  • ALPHABETR

    Researchers at the University of Glasgow have developed a computational method for fully characterising the T cell receptors (TCRs) in antigen-responsive cell populations.

    Expires: Created:
  • Blocking substrate recruitment by DHHC-protein acyl transferase enzymes for therapeutic gain

    Researchers at the University of Dundee have discovered and validated a novel approach for targeting an important class of enzymes with wide activity and linkage to disease.

    Expires: Created:
  • Anti-Nematode Therapeutics for Livestock Health

    Researchers at the University of Glasgow have developed Anti-Nematode Therapeutics, which have the potential to be used to treat parasitic nematodes which can cause major problems for livestock farming.

    Expires: Created:

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