Results For: "drug"

Showing 1 - 10 of 16 opportunities

  • Potential treatment for allergic disease including severe steroid resistant asthma

    A novel approach shows promising results as a potential therapeutic for allergic conditions, including severe steroid resistant asthma. A peptide has been identified, HpARI, that inactivates and inhibits release of IL-33 a critical step in the development of allergic disease.

    Expires: Created:
  • Novel and selective inhibitors of SRC family kinases

    Novel compounds displaying high potency and selectivity toward SRC family kinases have been developed. The lead compound eCF506 displays subnanomolar potency against SRC, high selectivity over ABL kinase (1000-fold), optimal pharmacokinetic profile and in vivo target engagement.

    Expires: Created:
  • App for accurate detection and monitoring of delirium

    Delirium is an acute and severe deterioration in mental function, which affects attention and cognition and poses a significant health problem for older patients in hospital. DelApp is a novel app based cognitive test, which can objectively detect delirium in patients.

    Expires: Created:
  • FluPep - Peptide-based therapy of influenza virus infection

    This anti-influenza therapy offers potential as anti-viral treatment as well as prevention against all major flu strains, including influenza A infection.

    Expires: Created:
  • Method for generating large quantities of mast cells for use in allergy drug research

    An improved method for robust and rapid production of large quantities of homogeneous mast cells suitable for research, drug discovery and cell therapy to treat allergy, anaphylaxis and autoimmune disorders.

    Expires: Created:
  • New prodrug strategy for targeted chemotherapies

    This new approach converts chemotherapy agents into prodrugs, significantly reducing systemic toxicity, and enabling local activation only at tumour sites where a specific catalyst, palladium, has been implanted.

    Expires: Created:
  • Sperm Motility Enhancers for Assisted Reproductive Technology

    Sperm Motility Enhancers: A Novel Strategy for Assisted Reproductive Technology (ART) based on the direct relationship between human fertility and sperm motility,the University of Dundee has successfully identified FDA-approved compounds with robust and effective stimulation on patient sperm motilit...

    Expires: Created:
  • Strategy for Enhancing the Performance of Vaccines

    Researchers at the University of Dundee have designed and synthesised a novel, multifunctional protease inhibitor that has the potential to significantly enhance the performance of vaccines through proteolytic modulation.

    Expires: Created:
  • Novel chemical probes of epigenetic protein function

    Researchers at the University of Dundee have developed a robust and original method for interrogating the activity of single bromodomain proteins, which will assist in exploring their role in the epigenetics of health and disease.

    Expires: Created:
  • Novel adjunct therapy to eliminate opioid tolerance and mitigate side effects

    Researchers at the University of Dundee have identified an adjunct to opioid therapy that suppresses the development of tolerance and may mitigate other severe side effects associated with opioid use.

    Expires: Created:

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