Results For: "drug"

Showing 1 - 10 of 13 opportunities

  • Sperm Motility Enhancers for Assisted Reproductive Technology

    Sperm Motility Enhancers: A Novel Strategy for Assisted Reproductive Technology (ART) based on the direct relationship between human fertility and sperm motility,the University of Dundee has successfully identified FDA-approved compounds with robust and effective stimulation on patient sperm motilit...

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  • Strategy for Enhancing the Performance of Vaccines

    Researchers at the University of Dundee have designed and synthesised a novel, multifunctional protease inhibitor that has the potential to significantly enhance the performance of vaccines through proteolytic modulation.

    Expires: Created:
  • Novel chemical probes of epigenetic protein function

    Researchers at the University of Dundee have developed a robust and original method for interrogating the activity of single bromodomain proteins, which will assist in exploring their role in the epigenetics of health and disease.

    Expires: Created:
  • Novel adjunct therapy to eliminate opioid tolerance and mitigate side effects

    Researchers at the University of Dundee have identified an adjunct to opioid therapy that suppresses the development of tolerance and may mitigate other severe side effects associated with opioid use.

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  • Biomarker assay to enable safe corticosteroid withdrawal

    Using hypothesis-free metabolomics screening, a list of seven biomarkers has been identified that, when combined, are highly sensitive in predicting corticosteroid dose and, thus, the risk of adrenal insufficiency on corticosteroid withdrawal. Quantitative assays for these metabolites will create a ...

    Expires: Created:
  • Bacterial Strains for Antibiotic Drug Discovery

    This technology consists of 12 K. pneumoniae strains that which have been genetically engineered to carry mutations affecting key cell functions known to be implicated in the development of drug resistance including antimicrobial efflux, virulence, transcription factor regulation and membrane stabil...

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  • Combination Treatment for MRSA Nasal Carriage and MRSA-infected Wounds

    The new treatment is a combination of a peptide (ranalexin) with bacteria cell wall-digesting protein (lysostaphin), which specifically targets and kills Staphylococcus aureus, including MRSA.

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  • Synergistic antifungal combination

    Candida species are a major cause of catheter-related nosocomial bloodstream infections. We have identified that the combination of an echinocandin antifungal with certain antimicrobial peptides results in potent, synergistic inhibition of yeast pathogens in vitro, so offering a potential combinatio...

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  • Chiral Rotational Spectroscopy

    Researchers at the University of Glasgow have developed a new technology to determine rotational transitions of molecules.

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  • Macrophage-based cell therapy to treat acute liver injury

    A novel cell-based therapeutic intervention to treat patients suffering from acute episodes of liver injury. When injected into patients showing acute or drug-induced liver injury, alternatively-activated macrophages could promote liver repair, by reducing cell death, stimulating hepatocyte prolifer...

    Expires: Created:

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