Results For: "cell"

Showing 11 - 20 of 35 opportunities

  • Chimaeric Innate Immune Receptors (CIIRS)

    A novel technology allowing targeting of cancer cells using the innate immune system

    Expires: Created:
  • A potential therapeutic approach to Spinal Muscular Atrophy (SMA)

    The neurodegenerative inherited disease Spinal Muscular Atrophy (SMA) is the leading genetic cause of infant mortality, affecting 1:6,000 live births. SMA causes a loss of spinal motor neurons and is characterised by progressive muscular atrophy.

    Expires: Created:
  • Topology specific security holograms

    The most prominent high security holographic anti-counterfeiting techniques include dot-matrix holograms and electron beam defined holograms. Both techniques require laser illumination, and the image can be viewed with a screen, CCD, or directly by the human eye.

    Expires: Created:
  • One step prodrug trigger for targeted release of drugs

    A tetrazine small-molecule trigger for activating prodrugs has been developed. Active molecules, such as a therapeutic drug or imaging fluorophore, can be caged within a polymer nanoparticle for controlled release at a targeted site.

    Expires: Created:
  • Potential treatment for allergic disease including severe steroid resistant asthma

    A novel approach shows promising results as a potential therapeutic for allergic conditions, including severe steroid resistant asthma. A peptide has been identified, HpARI, that inactivates and inhibits release of IL-33 a critical step in the development of allergic disease.

    Expires: Created:
  • Novel and selective inhibitors of SRC family kinases

    Novel compounds displaying high potency and selectivity toward SRC family kinases have been developed. The lead compound eCF506 displays subnanomolar potency against SRC, high selectivity over ABL kinase (1000-fold), optimal pharmacokinetic profile and in vivo target engagement.

    Expires: Created:
  • App for accurate detection and monitoring of delirium

    Delirium is an acute and severe deterioration in mental function, which affects attention and cognition and poses a significant health problem for older patients in hospital. DelApp is a novel app based cognitive test, which can objectively detect delirium in patients.

    Expires: Created:
  • Combined light communication and energy harvesting from solar panel receivers

    A technology allowing solar panels to harvest light energy while also acting as the receiver elements of light-based communication links or networks. These self-powered nodes allow networks of communicating devices to be assembled within the Internet of Things, Sensor Network applications, and in po...

    Expires: Created:
  • FluPep - Peptide-based therapy of influenza virus infection

    This anti-influenza therapy offers potential as anti-viral treatment as well as prevention against all major flu strains, including influenza A infection.

    Expires: Created:
  • High accuracy, low blood volume microarray-based test for bacterial sepsis

    A host-directed diagnostic methodology, which uses only 30 μL of whole blood, and enables rapid and accurate detection of sepsis in neonates and other subjects. The test removes false negative results associated with current gold standard microbiological methods.

    Expires: Created:

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