Results For: "cell"

Showing 1 - 10 of 35 opportunities

  • A potential therapeutic approach to Spinal Muscular Atrophy (SMA)

    The neurodegenerative inherited disease Spinal Muscular Atrophy (SMA) is the leading genetic cause of infant mortality, affecting 1:6,000 live births. SMA causes a loss of spinal motor neurons and is characterised by progressive muscular atrophy.

    Expires: Created:
  • Topology specific security holograms

    The most prominent high security holographic anti-counterfeiting techniques include dot-matrix holograms and electron beam defined holograms. Both techniques require laser illumination, and the image can be viewed with a screen, CCD, or directly by the human eye.

    Expires: Created:
  • One step prodrug trigger for targeted release of drugs

    A tetrazine small-molecule trigger for activating prodrugs has been developed. Active molecules, such as a therapeutic drug or imaging fluorophore, can be caged within a polymer nanoparticle for controlled release at a targeted site.

    Expires: Created:
  • Potential treatment for allergic disease including severe steroid resistant asthma

    A novel approach shows promising results as a potential therapeutic for allergic conditions, including severe steroid resistant asthma. A peptide has been identified, HpARI, that inactivates and inhibits release of IL-33 a critical step in the development of allergic disease.

    Expires: Created:
  • Novel and selective inhibitors of SRC family kinases

    Novel compounds displaying high potency and selectivity toward SRC family kinases have been developed. The lead compound eCF506 displays subnanomolar potency against SRC, high selectivity over ABL kinase (1000-fold), optimal pharmacokinetic profile and in vivo target engagement.

    Expires: Created:
  • High throughput imaging of cellular forces

    Our novel micro-interferometer based force sensors provide direct, robust and non-destructive imaging of forces associated with various types of mechanical cell-substrate interaction. The new method requires no zero-force reference image, enables continuous, measurement of multiple cells on one subs...

    Expires: Created:
  • App for accurate detection and monitoring of delirium

    Delirium is an acute and severe deterioration in mental function, which affects attention and cognition and poses a significant health problem for older patients in hospital. DelApp is a novel app based cognitive test, which can objectively detect delirium in patients.

    Expires: Created:
  • CxxC domain for isolation and determination of methylation status of CpG islands

    A protein domain (CxxC) has been discovered, which is capable of specifically binding non-methylated CpG islands (CGIs). A method for generation of CpG island library and a simple two-step, column-based process have been developed using this protein domain to separate CGIs from bulk DNA.

    Expires: Created:
  • Combined light communication and energy harvesting from solar panel receivers

    A technology allowing solar panels to harvest light energy while also acting as the receiver elements of light-based communication links or networks. These self-powered nodes allow networks of communicating devices to be assembled within the Internet of Things, Sensor Network applications, and in po...

    Expires: Created:
  • FluPep - Peptide-based therapy of influenza virus infection

    This anti-influenza therapy offers potential as anti-viral treatment as well as prevention against all major flu strains, including influenza A infection.

    Expires: Created:

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