Highly-specific polyclonal antibody to Red Fluorescent Protein
Matched staining demonstrating the specificity of the RFP. Left panel shows a cell transfected with an RFP fusion protein. Right panel shows the matched immunostaining for the RFP-fusion protein with the antibodies
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LICENSING OPPORTUNITY:
Researchers at the University of Edinburgh have developed a highly-specific polyclonal antibody to Red Fluorescent Protein for detecting RFP-tagged proteins.
The majority of currently available RFP antibodies are made to peptide rather than whole protein immunogen. Consequently, they can often lack specificity and give high background signals.
The Edinburgh RFP antibodies are rabbit polyclonals made to whole RFP protein which gives them strong reactivity, good specificity and low background when used to detect RFP tagged proteins in cells/extracts. The fact that they are to a whole protein immunogen makes them particularly effective in detecting protein where fixation methods such as formaldehyde are used which preserve native protein structure (eg. formaldehyde).
These RFP antibodies are sensitive and specific for RFP, do not cross react with GFP and can be used to detect RFP tagged proteins in a range of biochemical applications.Key Benefits
- Antibody is made to whole protein immunogen rather than peptide
- Strong reactivity providing good signal strength
- No cross-reactivity with GFP
- Clean background in cell Lysates
Applications
- Western Blotting
- Immunocytochemistry
- Immunohistochemistry
- Immunofluorescence
- Affinity Chromatography
- Immunoprecipitation
IP Status
The University of Edinburgh is seeking interest from life science reagent companies to license this technology on a non-exclusive basis with a view to marketing and selling these reagents.
This technology is available to license under a standard non-exclusive license agreement via Click-thru Licensing at the University of Edinburgh.
View Click-thru Licensing Opportunity and License Agreement
If you would like further information about
this opportunity please fill out the form below. Your enquiry will
be passed on to the relevant University who will respond to you directly.
